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Selenoneine: Unpacking This Marine Antioxidant & Its Key Features

Selenoneine is a naturally occurring compound that contains selenium, an essential trace element. It is a selenium-containing derivative of ergothioneine, and it has been found mainly in the blood and tissues of tuna and other fish, especially in species that are high on the food chain.

Key Facts About Selenoneine:

  • Structure: It is a selenium analog of ergothioneine, meaning selenium replaces the sulfur atom normally found in ergothioneine.
  • Source: Primarily found in marine animals, particularly tuna, where it exists at high concentrations in red muscle tissue.
  • Function: Selenoneine acts as a potent antioxidant. It helps neutralize reactive oxygen species (ROS), which can damage cells.
  • Health Role: It may help protect cells from oxidative stress, which plays a role in aging and various diseases. Selenoneine is also being studied for its role in regulating selenium metabolism and removing toxic metals like methylmercury from the body.
  • Human Relevance: Though humans don’t produce it naturally, eating fish rich in selenoneine could provide this compound. Scientists are still studying how much of it is absorbed and used in the human body.

Research Highlights:

  • Selenoneine has been proposed to bind methylmercury in fish muscle and reduce its toxicity, potentially protecting both the fish and the humans who eat them.
  • It is more bioavailable (easily used by the body) than some other forms of selenium.
  • It may contribute to the health benefits of eating fish, especially related to antioxidant support.

In summary, selenoneine is a special selenium compound with strong antioxidant properties. It is mainly found in fish like tuna and may help protect cells and detoxify harmful substances.

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